Automated Nuclei Detection

Automated nuclei detection in fluorescence microscopy by HEDAR.

At Durham University, my PhD research focussed on the use of mathematical morphology to quantify biological and medical images. One such challenge was the automated detection of ellipse-like objects, such as cell nulcei, in fluorescence microscopy. Working with colleagues, I developed a new approach to identifying ellipses based on Hilbert-edge detection and ranging (HEDAR) and assumptions based on the shape on an ellipse.

My contribution to this work was funded by EPSRC.

Chas Nelson
Chas Nelson
LKAS Research Fellow in Data Science

Interdisciplinary scientist with a background in bioimaging and informatics.